Work

Size-controlled antimicrobial peptide drug delivery vehicles through complex coacervation

Year: 2024
Type: article
Abstract: -PMAA polymers with varying chain lengths or PMAA homopolymers in ternary complex coacervation systems with colistin. This results in size-tunable colistin-C3Ms, ranging, depending on the mixing ratios, from micellar sizes of 26 nm to 100 nm. With size tunability at rather narrow size distributions and high stability, ternary colistin-C3Ms offer potential advancements in C3M drug delivery, paving the way for more effective and targeted treatments for bacterial infections in precision medicine.
Source: Soft Matter
Authors: Thomas Daniel Vogelaar, Henrik Torjusen, Reidar Lund
Institution: University of Oslo
Language: English
Subfield: Biomaterials
Open Access status: hybrid
OpenAlex ID: W4405727461
FWCI: 0.837
Cites: 75
Cited by: 10
Related to: 10