Work

Left atrial remodeling and voltage-guided ablation outcome in persistent atrial fibrillation patients over 75 years of age

Year: 2024

Type: article

Abstract: Background: The prevalence of atrial fibrillation (AF) increases with age. The improvement in ablation techniques has widened the indications, particularly in elderly patients. Data on LA remodeling and low-voltage zone (LVZ) extent in this subgroup are scarce. Objective: We assessed the left atrial (LA) bipolar voltage, LVZ extent, and efficacy of voltage-guided ablation in a cohort of patients with persistent AF according to age. Methods: was defined as <0.5 mV. A propensity score-matching analysis was used to assess the impact of age on LA remodeling. Results: <.001) were predictive of LVZ presence. After 36 months of follow-up, the AF-free survival rate after a single procedure was similar between the 2 groups. Conclusion: Patients >75 years of age with persistent AF display increased LA substrate remodeling than do younger patients. LA scar did not seem to negatively affect the results of substrate-guided ablation, and the complication rate was low.

Source: Heart Rhythm O2

DOI: 10.1016/j.hroo.2024.12.006