Work

Network-wide effects of pallidal deep brain stimulation normalised abnormal cerebellar cortical activity in the dystonic animal model

Year: 2024

Type: article

Abstract: BACKGROUND: hamster. METHODS: hamsters were analysed. A nonlinear data-driven method characterised the low-dimensional representation of the patterns in MEA data. RESULTS: . CONCLUSIONS: hamsters could be a hint of a decrease in neuronal fibres and synaptic plasticity. Treatment with pallidal DBS led to cerebellar cortical activity similar to healthy controls, displaying the network-wide impact of local stimulation.

Source: Neurobiology of Disease

DOI: 10.1016/j.nbd.2024.106779