A new sesquiterpene from the heartwood of Cordia trichotoma (Vell.) Arráb. ex Steud
Year: 2024
Type: article
Abstract: A new sesquiterpene, 8,11-epoxy-cadi-3,9-diene (1), along with nine known compounds (2–10), were isolated from the heartwood of Cordia trichotoma. Their structures were elucidated based on NMR spectroscopic data, and by comparison with data previously reported in literature. The hexane extract from the heartwood of C. trichotoma, the EtOH extract from the heartwood of C. trichotoma, the CH2Cl2-soluble fraction of the EtOH extract, the EtOAc-soluble fraction of the EtOH extract and the compounds 1–6 have been evaluated as acetylcholinesterase inhibitors, and among these, the extracts and fractions exhibited satisfactory results. In addition, compounds 5, 7, and 8 have not been reported previously from this genus.
Source: Natural Product Research
Authors: Francisca Roziane Severino Lopes, Francisco das Chagas Lima Pinto, Horlando Carlota da Silva, Francisco Mateus Gomes do Nascimento, Maria Teresa Salles Trevisan, Otília Deusdenia Loiola Pessoa, Gilvandete Maria Pinheiro Santiago
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4405761711