Year: 2024
Type: article
Abstract: Diabetes mellitus is a serious metabolic disorder characterized by elevated blood glucose levels resulting from either autoimmune destruction of β-cells in the pancreatic islets or insulin resistance. Type 1 diabetes mellitus is currently managed with insulin therapy; however, long-term treatment is often associated with chronic complications such as limb amputation, blindness, and kidney failure. This review explores innovative therapeutic strategies for Type 1 diabetes mellitus based on a comprehensive literature search using PubMed and relevant keywords. The findings highlight several promising approaches, including gene therapy, trans-differentiation, enhancing the self-replication of β-cells, stem cell therapies, immunomodulatory agents, and herbal medicines, all of which show potential for improving disease management and reducing complications.
DOI: 10.62810/jns.v7i3.63
Author: Qand Agha Nazari
Institution: Kabul University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4405762426