Year: 2024
Type: article
Abstract: GG (LGG) improves intestinal health in humans. However, in zebrafish, the SpaC pilin of LGG and the LPS produced by SpaC-induced dysbiotic gut microbiota cause intestinal pyroptosis and epithelial damage. This negative effect is host-specific, raising concerns about the safety of using classical terrestrial-derived probiotics strains in aquatic species. These results emphasize the need for species-specific probiotic evaluations and promote the regulation of non-host origin probiotics in aquaculture. Further research is needed to understand the action mechanisms of non-host probiotics and their impacts on economical fish species.
Source: iMetaOmics.
DOI: 10.1002/imo2.47
Author: Einar Ringø
Institution: UiT The Arctic University of Norway
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4405764809