Evaluation of Effect of Split Administration of Compound Polyethylene Glycol Electrolyte Powder Combined With Simethicone Oil in Bowel Preparation Before Colonoscopy in the Elderly
Year: 2024
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Objective This study is to explore the application value of fractional administration of compound polyethylene glycol electrolyte powder combined with simethicone for bowel preparation before colonoscopy in elderly patients. Methods The objects are 60 elderly patients who underwent colonoscopy in our hospital in 2021. The patients were randomly divided into the control group and the observation group, with 30 cases in each group. The control group took two doses of polyethylene glycol electrolyte powder eight hours apart for intestinal preparation. On this basis, the observation group was given simethicone for bowel preparation. Adverse reactions, intestinal cleanliness, air bubbles in the intestines, lens clarity, time of entering the lens, amount of saline flushing, and lesion detection were compared between the two groups. Results There was no significant difference in adverse reactions, bowel cleanliness score, detection rate of ≥0.5 cm polyps, and adenomas between the two groups (P > 0.05), but the air bubbles and lens clarity, the time of entering the lens, amount of saline flushing, detection rate of <0.5 cm polyps of the observation group was significantly better than that of the control group (P < 0.05). Conclusion It is safe and effective for elderly patients to take compound polyethylene glycol electrolyte powder combined with simethicone for intestinal preparation.
Source: International Surgery
Authors: Yanfang Sun, Ying Liu, Yanna Xie, Yisha Zhang, Hongyan Yang, Yong Yang, Aihua Wang
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405793735