Work

Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis

Year: 2024

Type: article

Abstract: The retrospective study was conducted at Baoding No.1 Central Hospital, China, and comprised data from July 2021 to January 2023, and aimed at exploring the relationship of neuron-specific enolase, D-dimer and lactate dehydrogenase with prognosis in patients with serous traumatic brain injury. Data of 100 patients was categorised into favourable prognosis group A having 50(50%) patients and unfavourable prognosis group B having 50(50%) patients, and was compared with as many healthy controls in group C. Increase in neuron-specific enolase, D-dimer and lactate dehydrogenase concentrations was significantly elevated in groups A and B compared to group C (p<0.05), and in group B compared to group A (p<0.05).

Source: Journal of the Pakistan Medical Association

DOI: 10.47391/jpma.11088

Authors: Jing Xie, Lu Zhang, Ning Gan

Institution: Baoding No.1 Central Hospital

Language: English

Topic: Traumatic Brain Injury and Neurovascular Disturbances

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $650