Work

Development of a software architecture for bioprocess modeling

Year: 2024

Type: article

Abstract: Increasing the productivity of a biotechnological process becomes feasible through the development of Process Systems Engineering tools, which integrate experimental data with mathematical modeling. This work aims to develop a software architecture for modeling bioprocesses that is accessible to a multidisciplinary group. To achieve this aim, the software must be thoroughly designed based on an ontology that describes bioprocesses that can be apprehended by researchers from different fields. The ontological representation is carried out using Unified Modeling Language diagrams, whose use is demonstrated by a parameter estimation case study. It is concluded that good software development practices can be provided through the proposed architecture, since it guides simulations and parameter estimations of biotechnological processes in a structured way. • Ontological representation of bioprocesses using Unified Modeling Language diagrams. • Code developed in a generic way for (re)use by different bioprocess users. • Code implementation in open-source languages Julia and JuMP.

Source: Digital Chemical Engineering

DOI: 10.1016/j.dche.2024.100210

Authors: Priscila Marques da Paz, Caroline Satye Martins Nakama, Galo Antonio Carrillo Le Roux

Institutions: Universidade de São Paulo, Norwegian University of Science and Technology

Language: English

Topic: Model-Driven Software Engineering Techniques

Subfield: Software

Field: Computer Science

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,800

OpenAlex ID: W4405802399

FWCI: 2.131

Cites: 34

Cited by: 2

Related to: 10