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From skin to heart: The rare journey of pleomorphic dermal sarcoma metastasis

Year: 2024
Type: article
Study design: Case Report
Abstract: Cardiac tumours can be classified as neoplastic or non-neoplastic, with secondary tumours being significantly more common than primary ones. Among secondary tumours, melanoma has the highest propensity for cardiac involvement. Pleomorphic dermal sarcoma (PDS) is a rare skin neoplasm, with an estimated metastatic risk of 10% to 20%. This report presents the case of a 52-year-old male who, after a history of PDS, developed cardiac metastasis 4 years postexcision. Despite clear surgical margins and adjuvant radiotherapy, he later exhibited metastatic disease affecting the lungs and heart. Advanced imaging revealed tumour invasion into the left atrium, leading to palliative chemotherapy and ultimately the patient's transition to palliative care 7 months after diagnosis. This case underscores the need for vigilance in monitoring potential metastasis in rare tumours like PDS.
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $550
OpenAlex ID: W4405802592
FWCI:
Cites: 9
Cited by:
Related to: 10