Work

The molecular features of non-peptidic nucleophilic substrates and acceptor proteins determine the efficiency of sortagging

Year: 2024

Type: article

Abstract: Investigation of the influence of the structural and physico-chemical features of proteins and non-peptidic incoming nucleophilic components on the efficiency of Sortase A-mediated C-terminal protein bioconjugations is presented.

Source: RSC Chemical Biology

DOI: 10.1039/d4cb00246f

Authors: Tetiana Bondarchuk, Elena Zhuravel, Oleh Shyshlyk, Mykhaylo O. Debelyy, Oleksandr Pokholenko, Diana Vaskiv, Alla Pogribna, Mariana Kuznietsova, Yevhenii Hrynyshyn, Oleksandr Nedialko, Volodymyr Brovarets, Sergey A. Zozulya

Institutions: Enamine (Ukraine), Institute of Molecular Biology and Genetics, Institute of Bioorganic Chemistry and Petrochemistry V.P. Kukhar, Taras Shevchenko National University of Kyiv, V. N. Karazin Kharkiv National University

Language: English

Topic: Biochemical and Structural Characterization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,962

OpenAlex ID: W4405803698

FWCI: 0.117

Cites: 51

Cited by: 1

Related to: 10