Year: 2024
Type: article
Abstract: Hair follicle stem cells (HFSCs) exhibit significant potential in hair regeneration research due to their self-renewal and multi-directional differentiation abilities. Hair loss is a common dermatological issue, and current treatment methods have limited efficacy; however, the investigation of HFSCs offers new avenues for developing novel therapies. HFSCs are relatively easy to isolate and culture from hair follicles, making them ideal candidates for laboratory and clinical applications. In addition to their role in hair regeneration, HFSCs contribute to the regeneration of skin, bone, cardiovascular, and neural tissues. Nonetheless, challenges remain regarding the effective expansion of HFSCs, their survival rates, and functional recovery in vivo. Furthermore, further research is needed to elucidate the specific mechanisms by which HFSCs operate in various types of hair loss. Overall, stem cells hold significant promise in the field of hair regeneration, and with a deeper understanding of HFSC biology and advancements in related technologies, more effective hair loss treatment strategies are anticipated in the future.
DOI: 10.54097/pzw62505
Author: Xinyu Mu
Institution: Guangzhou Institute of Science and Technology
Language: English
Topic: Hair Growth and Disorders
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405809114