Year: 2024
Type: article
Study design: Case Report
Abstract: More recently, clinically-appearing atypical blue nevi which have been biopsied have been read by dermatopathologists as melanocytomas. We have noticed this phenomenon over the last 1-2 years. The spectrum between blue nevi, atypical blue nevi and melanocytomas seems to be blurry. With the advent of newer immunohistochemistry stains including, but not limited to, PRAME, Mel/Ki-67, p16 and BAP1; there have been more outright calls of melanocytomas. Below we describe three cases which, to us as clinicians, are an enigma. The proliferation of these immunostains – while it has helped in malignant differentiation – seems to also lead to confusing diagnoses.
Source: Journal of Dermatology Research
Authors: Edward M Klepper, Danielle M Auth, Katie M Hodges, Maria L Andrzejewski, Ahmed M Sikder, Kishore E Clark, Jonathan J Lee, Howard N Robinson
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4405809573