Work

Discovery and biological evaluation of nitrofuranyl–pyrazolopyrimidine hybrid conjugates as potent antimicrobial agents targeting Staphylococcus aureus and methicillin-resistant S. aureus

Year: 2024

Type: article

Abstract: Nitrofuranyl–pyrazolopyrimidine conjugates exhibiting potent in vitro and in vivo efficacy against Gram-positive bacterial strain S. aureus and its resistant variant methicillin-resistant S. aureus .

Source: RSC Medicinal Chemistry

DOI: 10.1039/d4md00826j

Authors: Sapna Saini, G. Lakshma Reddy, Anjali Gangwar, Harpreet Kour, Gajanan G. Nadre, Ramajayan Pandian, Sunny Pal, Utpal Nandi, Rashmi Sharma, Sanghapal D. Sawant

Institutions: Indian Institute of Integrative Medicine, Academy of Scientific and Innovative Research, National Chemical Laboratory, Bose Institute

Language: English

Topic: Synthesis and Characterization of Heterocyclic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Department of Science and Technology, Ministry of Science and Technology, India, Council of Scientific and Industrial Research, India, Science and Engineering Research Board

Awards: G2534700558, G30689110

OpenAlex ID: W4405818187

FWCI: 0.424

Cites: 67

Cited by: 3

Related to: 10