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Study of hepatoprotective properties of protein fractions obtained from leaves of Tagetes erecta L. and Salvia aethiopis L. plants by gel filtration chromatography on tetrachloromethane (CCl4) damaged hepatocytes of mice

Year: 2024

Type: article

Abstract: The study presents data on the action of protein fractions obtained from Tagetes erectaL. and Salvia aethiopisL. plants by gel filtration chromatography on the hepatocytes of mice damaged by a 10% tetrachloromethane solution. Protein fractions of the third and fourth peaks have weak hepatoprotective properties. Each peak was also separated into several fractions by the method of ion exchange chromatography. The SDS-PAGE revealed fractions, including those with a molecular weight of 23-47 kDa, which probably participate in the protection of hepatocytes.

Source: MODERN ISSUES OF MEDICINE AND MANAGEMENT

DOI: 10.56580/geomedi47

Authors: Marina Pirtskhalava, Malkhaz Vakhania, Teimuraz Tavkhelidze, Marina Gogodze, Mariam Kobiashvili, Tornike Mindiashvili

Institution: University Geomedi

Language: English

Topic: Drug-Induced Hepatotoxicity and Protection

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405826972

FWCI:

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Related to: 10