Chronic C Hepatitis with Hepatocellular Carcinoma
Year: 2024
Type: article
Study design: Case Report
Abstract: Nowadays chronic C hepatitis is a common infectious disease worldwide. Complications of this disease include: liver cirrhosis, acute and subacute live failure (hepatic encephalopathy, portal vein hypertension, ascites, hepatorenal syndrome), hepatocellular carcinoma (HCC). Since 2015 there is C-elimination program in Georgia, in which patients with chronic C hepatitis can be treated with antiviral drugs for 3,6 or 12 months. Although after antiviral therapy majority of patients get rid of the C hepatitis virus, due to liver damage (high, moderate or low) it is possible for patients to develop complications of chronic C hepatitis, including hepatocellular carcinoma. In our case report we present you 58-year-old patient, who was diagnosed with chronic C hepatitis in 2016 complicated with liver cirrhosis. Antiviral treatment was performed. Virus was eliminated, i.e. a solid viral respond was obtained. Due to liver damage he was hospitalized in the Center of infectious diseases, AIDS and clinical immunology, where he was diagnosed with HCC. The patient has been under constant monitoring until and AFP (alpha-fetoprotein), which is a marker of hepatocellular carcinoma, has always been within the normal range at <5.8 IU/ml. And with the last determination of AFP in the blood, the result was obtained >1000 IU/ml.
DOI: 10.56580/geomedi51
Authors: Maia Akhvlediani, Maia Zhamutashvili, Marina Endeladze, Ketevan Meskhi, Elene Shengelia
Language: English
Topic: Hepatitis C virus research
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405829994