Improving the bioactivity and mechanical properties of poly(ethylene glycol)-based hydrogels through a supramolecular support network
Year: 2024
Type: article
Abstract: formation of nanofiber networks can tune the stiffness of PEG-based hydrogels, while also imparting shear thinning, stress relaxation, and self-healing properties. The hybrid networks show enhanced toughness and durability under tension, providing scope for use in load bearing applications. A small quantity of Trpzip peptide renders the non-adhesive PEG network adhesive, supporting adipose derived stromal cell adhesion, elongation, and growth. The integration of supramolecular networks into covalent meshworks expands the versatility of these materials, opening up new avenues for applications in biotechnology and medicine.
Source: Journal of Materials Chemistry B
DOI: 10.1039/d4tb02002b
Authors: Yuzhu Liu, Md Shariful Islam, Anna Bakker, Zihao Li, Alaa Ajam, Jamie J. Kruzic, Kristopher A. Kilian
Institution: UNSW Sydney
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4405839768