Synergistic effect of Camel milk and Hibiscus rosa sinensis on the reproduction of Type II diabetic albino Wistar rats
Year: 2024
Type: article
Abstract: Diabetes adversely affects male reproduction and closely associated with male infertility. The present study designed to assess the synergistic effects of Camel milk and Hibiscus rosa sinensis on the reproduction of type II diabetic Wistar rats over one month. Rats were divided into seven groups: control (Group I) and diabetic control (Group II). Group III received 125 mg/kg/day H. rosa sinensis, whereas Group IV received 50 ml/rat/day Camel milk. Groups V–VII were treated synergistically with varying H. rosa sinensis and Camel milk dosages. Group II showed persistent hyperglycemic state, gradually decreasing in treatment groups (III-IV) and synergistic groups (V-VII). The pancreas of Group II rats was damaged, including acinar cell necrosis and vacuolation. These damages were significantly improved in treatment groups (III-IV) and synergistic groups (V-VII). Group II male rats exhibited significant damage to their seminiferous tubules, including a decrease in diameter, and loss of spermatozoa. Seminiferous tubule structures were significantly improved in treatment groups III & IV. The 1st synergistic group (V) demonstrated greater recovery of altered seminiferous tubule structures than the 2nd and 3rd synergistic groups (VI and VII). Sperm analysis revealed that Group II animals had significantly reduced sperm count, motility, and viability, whereas treatment groups III-IV had better sperm characteristics. The synergistic group (V) had a greater sperm count, motility, and viability than synergistic groups (VI and VII). The present study showed synergistic benefits of H. rosa sinensis and Camel milk in treating and reproducing type II diabetic rats at very low doses.
Authors: K. Chauhan, S. Rani
Institution: Maharshi Dayanand University
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405839815