Work

Reaction of Tetrahydropyrimidine-2(1H)-thione Derivatives with Thiolated Acid Hydrazides as a Method of Synthesis of Biologically Active Ligands of Gold Glyco-Nanoparticles

Year: 2024

Type: article

Abstract: The reaction of 4-hydroxy-1-phenyl-6-methyltetrahydropyrimidine-2(1H)-thione with 6-mercaptohexanoic and lipoic (thioctic) acids hydrazides in yields of 60–75% to form 4-[ω-(mercaptoacyl)hydrazino]-tetrahydropyrimidine-2(1H)-thiones as a promising сo-ligands for the preparation of gold glyco-nanoparticles for biomedical purposes.

Source: Журнал органической химии

DOI: 10.31857/s0514749224020041

Authors: A. Y. Ershov, I. V. Lagoda, A. A. Martynenkov, A. A. Batyrenko

Institutions: Russian Academy of Sciences, Institute of Macromolecular Compounds, Ministry of Defence of the Russian Federation

Language: English

Topic: Gold and Silver Nanoparticles Synthesis and Applications

Subfield: Electronic, Optical and Magnetic Materials

Field: Materials Science

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W4405844731

FWCI:

Cites: 5

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Related to: 10