Synthesis of Spiro[indole-3,2′-pyrrole]triones by the Reaction of Pyrrolobenzoxazepinetriones with Enaminoketone
Year: 2024
Type: article
Abstract: The reaction of 3-aroylpyrrolo[1,2-a][4,1]benzoxazepin-1,2,4-triones with 3-cyclohexylamino-5,5-dimethylcyclohex-2-en-1-one leads to the formation of 3′-(4-aroyl)-4′-hydroxy-1′-(2-(hydroxymethyl)phenyl)-6,6-dimethyl-1-cyclohexyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones. A new scheme for the interaction of 3-aroylpyrrolo[1,2-а][4,1]benzoxazepine-1,2,4-triones with N-substituted enaminoketones leading to the formation of derivatives of the difficult-to-reach heterocyclic systems of spiro[indole-3,2′-pyrrole]triones is described.
Source: Журнал органической химии
Institution: Perm State University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4405844745