Year: 2024
Type: article
Abstract: Introduction: The children’s resistance to dosage regimens is one of the challenging issues in pediatric therapy. There are two significant issues with pediatric patients: a lack of self-drug administration skills and patient compliance. The medical characteristics of herbs have become increasingly important due to their lack of side effects, low cost, and biocompatibility. Method: The herbs that will be used are Ocimum sanctum (Tulsi), Adhatoda vasika (Adulsa), Elettariacardamomum (Cardamom), Zingiberofficinale (Ginger), Mentha piperita (Peppermint), Glycyrrhiza glabra (Liquorice), Eugenia caryophyllus (Clove), Cinnamomum zeylanicum (Cinnamon), and Honey. The formulation were prepared by decoction method and evaluated. Results: These herbs’ extracts show good antimicrobial activity against E. coli. The formulated jelly shows good appearance, pH, disintegration, and spreadability. We conduct a 6-month stability study on the formulated jelly. It has a good appearance and does not change pH. So, the formulated jelly can be stable for up to 6 months. Conclusions: The data revealed that the optimized formulation had not shown any change in their appearance or pH. So, the formulated jelly can be stable for up to 6 months. The formulations exhibited excellent antimicrobial activity, which is suitable to administer to children as an alternative oral solid dosage form.
Source: Ars Pharmaceutica (Internet)
Authors: Khemchand Surana, Vaishali Sonawane, Chaitali Yeola, Jayesh Musale, Sunil Mahajan, Deepak Sonawane, Vijayraj Sonawane, Raj Keservani
Institution: Savitribai Phule Pune University
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Funder: Universidad Nacional de Colombia
OpenAlex ID: W4405849860