Year: 2024
Type: article
Abstract: The prevalence of older adults living with obesity is increasing (39%) and their quality of life is diminished by multimorbidity, mobility disability, and frequent healthcare visits. Common comorbidities include cardiometabolic, pulmonary, liver and kidney diseases, memory loss, mental health conditions, and cancers. Multimorbidity leads to polypharmacy burden while necessitating care by multiple specialists. The heterogeneity of aging with cumulative disease burden due to obesity further accelerates aging by the dynamic accumulation of biological changes predisposing to geriatric syndromes. This physiological process increases the risk of functional limitation, mobility disability, and early institutionalization. Earlier in life, older adults with obesity often have attempted intensive lifestyle intervention (ILI) including diet and physical activity changes, trialed first-generation anti-obesity medications (AOMs), and a few have undergone weight loss surgery. With aging and obesity, they are faced with multimorbidity and disability and hence have patient-priority goals for weight loss and overall health.
DOI: 10.1111/jgs.19353
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,760
OpenAlex ID: W4405857947