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One‐Pot Sequential Four‐Component Reaction for the Synthesis of Novel Dihydro Oxaphospholo Pyrazole 2‐Oxides in Acetic Acid Medium

Year: 2024

Type: article

Abstract: ABSTRACT A four‐component one‐pot sequential approach to five‐membered oxaphosphaheterocycles have developed. The method involves in situ generation of methylpyrazolin‐5‐one from ethyl acetoacetate and phenyl hydrazine. Further, a sequential reaction of methylpyrazolin‐5‐one with various aromatic aldehydes and phenyl dichloro phosphine afforded dihydro oxaphospholo pyrazole 2‐oxide derivatives.

Source: Journal of Heterocyclic Chemistry

DOI: 10.1002/jhet.4946

Authors: Mingshu Wu, Zhengfan Sun, Rui Ning, Ziwen Yan, Junying Ma, Siqi Fan

Institutions: Hainan Vocational University of Science and Technology, Hainan Normal University

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W4405884212

FWCI: 0.141

Cites: 43

Cited by: 1

Related to: 10