Work

Field-free Line Magnetic Particle Imaging: Radon-based Artifact Reduction with Motion Models

Year: 2024

Type: article

Abstract: Magnetic particle imaging is a promising medical imaging technique. Applying changing magnetic fields to tracer material injected into the object under investigation results in a change in magnetization. Measurement of related induced voltage signals enables reconstruction of the particle distribution. For the field-free line scanner the scanning geometry is similar to the one in computerized tomography. We make use of these similarities to derive a forward model for dynamic particle concentrations. We validate our theoretical findings for synthetic data. By utilizing information about the object’s dynamics in terms of a diffeomorphic motion model, we are able to jointly reconstruct the particle concentration and the corresponding dynamic Radon data without or reduced motion artifacts. Thereby, we apply total variation regularization for the concentration and an optional sparsity constraint on the Radon data.

Source: Sensing and Imaging

DOI: 10.1007/s11220-024-00524-y

Authors: Stephanie Blanke, Christina Brandt

Institutions: Universität Hamburg, Universität Greifswald

Language: English

Topic: Characterization and Applications of Magnetic Nanoparticles

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,390

Funders: Deutsche Forschungsgemeinschaft, Universität Hamburg