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Investigating Extracellular Vesicles in Viscous Formulations: Interplay of Nanoparticle Tracking and Nanorheology via Interferometric Light Microscopy

Year: 2024

Type: article

Abstract: Extracellular Vesicles Nanoparticle tracking analysis by interferometric light microscopy is a methodology for analyzing the concentration and size distribution of nanoparticles. Interference patterns analysis enables nanoparticle tracking not only in aqueous solutions but also in complex, high viscosity or non-Newtonian media, particularly pertinent for characterizing extracellular vesicle formulations and to evaluate their interactions with their local environment through a nanorheological approach. More in article number 2400319, Lucile Alexandre, Kelly Aubertin, and co-workers.

Source: Small Science

DOI: 10.1002/smsc.202570003