Get started
Work

Functionalization of Silica Nanoparticles for Tailored Interactions with Intestinal Cells and Chemical Modulation of Paracellular Permeability

Year: 2024
Type: article
Abstract: Paracellular Permeability In article number 2400112, Giorgia Del Favero, Freddy Kleitz, and co-workers explored the interactions of tailored functionalized silica nanoparticles with intestinal cells. Diversification of surface chemistry enabled modulation of paracellular permeability and transient barrier relapse in a differentiated Caco-2/HT29-MTX-E12 coculture model. These effects were associated with the reorganization of tight junction proteins and an increase in cell-cell distances induced by particle treatments.
DOI: 10.1002/smsc.202570001
Authors: Claudia Iriarte‐Mesa, Janice Bergen, Kristina Danielyan, Francesco Crudo, Doris Marko, Hanspeter Kählig, Giorgia Del Favero, Freddy Kleitz
Language: English
Subfield: Neurology
Open Access status: gold
Estimated APC paid: $5,770
OpenAlex ID: W4405912689
FWCI: 0.136
Cites:
Cited by: 1
Related to: 10