How accurate is ceftriaxone at predicting susceptibility of enterobacterales isolates to oral higher-generation cephalosporins?
Year: 2024
Type: article
Abstract: ABSTRACT The reliability of ceftriaxone for inferring susceptibility to higher-generation oral cephalosporins is unknown. Overall, ceftriaxone susceptibility predicted susceptibility to cefuroxime (89%), cefdinir (86%), cefpodoxime (90%), and cefixime (94%) based on disk diffusion results for 409 consecutive Enterobacterales bloodstream isolates from unique patients. Susceptibility percentages to the four oral cephalosporins ranged from 92% to 99% when limited to Escherichia coli , Klebsiella pneumoniae, Klebsiella oxytoca, or Proteus mirabilis isolates susceptible to ceftriaxone.
DOI: 10.1128/aac.01387-24
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: hybrid
Award: G1047260338
OpenAlex ID: W4405920982