Catalytic Difunctionalization of Alkenes under Visible Light Irradiation: Synthesis of Iminofuranones
Year: 2024
Type: article
Abstract: Comprehensive Summary Here, we show a cost‐effective and environmentally friendly method for synthesizing iminofuranones using visible light and the photocatalyst 2‐bromoanthraquinone. Our approach uses only oxygen as the oxidant, avoiding the need for additional transition metals and strong oxidizing agents. By employing a mixed solvent system of DMF and CHCl3 under ambient conditions, we have achieved highly diastereoselective conversions of various 2‐vinyl benzamides and alkenyl amides into functionalized iminoisobenzofuranones and iminofuranones. This versatile process is broadly applicable and enables late‐stage structural modifications of complex substrates with bioactive moieties.
Source: Chinese Journal of Chemistry
Authors: Boyu Liu, Guangxian Chen, Lele Zhang, Feiwei Yan, Feiming Li, Zhixiong Cai, Mingqiang Huang, Lina Cai, Shunyou Cai
Institutions: Minnan Normal University, Peking University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4405928973