Work

Assessing the relationship between liver and spleen volumes in patients with liver cirrhosis using the Cavalieri principle on cross-sectional images

Year: 2024

Type: article

Abstract: In the early stages of liver cirrhosis, hepatomegaly is observed, while in the later stages, enlargement of the spleen is observed due to shrinkage of the liver and increased pressure in the portal circulation. This study examined liver and spleen volumes and their proportional relationship to each other in healthy controls (HC) and patients with liver cirrhosis (LC) using computed tomography (CT) images. CT images of 52 LC (26 females, 26 males) and 52 HC (26 females, 26 males) aged 18 to 85 years were used. Liver and spleen volumes and spleen/liver+spleen volume ratio were calculated using the Cavalieri principle. Volume and ratio data were compared between HC and LC. In addition, volumes and ratios were evaluated according to the disease classes in patients. Liver volume was larger in LC (1488.9±502.3 cm3) than in HC (1321.8±277.1 cm3) (p=0.038). Spleen volume was also larger in LC (676.8±347.02 cm3) than in HC (249.37±101.16 cm3) (p

Source: DergiPark (Istanbul University)

Authors: Özgen, Merve Nur, Şahin, Abdurrahman, Yuksekkaya, Ruken, Şahin, Bünyamin

Institutions: Tokat Gaziosmanpaşa Üniversitesi, Sincan Training and Research Hospital, Ondokuz Mayıs University

Language: English

Topic: Liver Disease and Transplantation

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4405940945

FWCI:

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