The frequency and associated factors of erosive osteoarthritis in patients with rheumatoid arthritis
Year: 2024
Type: article
Study design: Observational Study
Abstract: Erosive osteoarthritis (EOA) is a deformative joint disease affecting small joints of hands that causes pain and disability, as does rheumatoid arthritis (RA). So, EOA may interfere with the assessment of RA disease activity. In this study, we aimed to determine the frequency and associated factors of EOA in patients with RA and pay attention to the overlap syndrome between RA and EOA. The electronic medical files of adult RA patients were reviewed retrospectively. Patients with another rheumatic diseases were excluded. Hand X-rays were read by two rheumatologists and one radiologist. Patients with RA were divided into two groups according to the presence of EOA. We totally analyzed 619 patients with a mean age of 54.2 years, and 82.8% of them were female. The 95.4% of patients had RA-type erosive changes according to the Modified Sharp Score. We found the frequency of EOA to be 6.3% in patients with RA. Erosive osteoarthritis was significantly higher in patients who had >50 years of age (p= 0.006), disease duration >10 years (p= 0.003), and anti-CCP negativity (p= 0.02) than in those without. In multivariable regression analysis, only age was the independent predictive factor for EOA (p
Source: DergiPark (Istanbul University)
Authors: Pekdiker, Mete, Korkmaz, İnan, Ketenci, Sertaç
Institutions: Mustafa Kemal University, Ondokuz Mayıs University
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4405940951