Work

Monoclonal Anti-CD47 Therapy and its Haematological Effects, including Anaemia and Thrombocytopenia

Year: 2024

Type: article

Abstract: Monoclonal anti-CD47 therapy is a new form of immunotherapy, which has been used in a clinical setting in recent years for the treatment of haematological and solid malignancies. Anti-CD47 functions by blocking the CD47-SIRPα interaction and promotes the phagocytosis of cancer cells, which attempt to invade the immune systems mechanisms via this interface.

Source: Emergency Medicine Trauma & Surgical Care

DOI: 10.24966/ets-8798/100070

Language: English

Topic: Phagocytosis and Immune Regulation

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405950407

FWCI:

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Related to: 10