Work

Synthesis of Linear 6-Allylated-7-hydroxycoumarins: para-Claisen Rearrangement of 2'-Allylated/Prenylated Derivatives of 4'-Prenyloxy Cinnamic Acid

Year: 2024

Type: article

Abstract: Linear 6-allylated-7-hydroxycoumarins were synthesized by the para-Claisen rearrangement of 4'-prenyloxy cinnamic acid derivatives under refluxing condition in N,N-diethylaniline. This method eliminates the requirement for an additional Lewis acid, such as boron trifluoride etherate or trichloride, to convert 7-alkoxycoumarins into 7-hydroxycoumarins, unlike alternative techniques.

Source: Asian Journal of Chemistry

DOI: 10.14233/ajchem.2025.32937

Author: Mrityunjoy Datta

Institution: Sarojini Naidu College for Women

Language: English

Topic: Synthesis of Organic Compounds

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: diamond

Funder: University of Kalyani

OpenAlex ID: W4405952683

FWCI:

Cites: 12

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Related to: 10