Year: 2024
Type: article
Study design: Case Report
Abstract: Cleidocranial dysplasia is a rare genetic disorder characterized by a congenital autosomal dominant condition.It leads to hypoplasia of the clavicles, abnormal formation of the teeth, and issues with skeletal and craniofacial bones.This condition is caused by a mutation in the Runt-related transcription factor 2, which is essential for the formation of teeth, cartilage, and bone.Patients with cleidocranial dysplasia exhibit typical polyostotic features, including underdeveloped clavicles, delayed closure of cranial fontanels and sutures, multiple woven bones in the skull, and dental anomalies such as failure of permanent tooth eruption, lack of deciduous tooth resorption, and multiple impacted and supernumerary teeth.This article presents a case of cleidocranial dysplasia in a 22-year-old female patient, aiming to highlight the clinical and radiological aspects of diagnosis.
Source: Oral Biology Research
Authors: Chang-Ki Min, Young-Mi Jeon, Kyoung-A Kim
Institution: Jeonbuk National University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
Funder: Jeonbuk National University
OpenAlex ID: W4405953486