Combined Phacoemulsification, Goniosynechialysis and Ab Interno Trabeculectomy in Primary Angle-closure Glaucoma: Long-term Results
Year: 2024
Type: article
Abstract: Objective: This research was designed to evaluate the efficacy and safety of ab-interno trabeculectomy (Trabectome and Kahook Dual Blade) combined with phacoemulsification, intraocular lens implantation, and goniosynechialysis in eyes with primary angle-closure glaucoma.Methods: A total of 47 patients were included in the study and all the patients received the combined surgery.Intraocular pressure, anti-glaucoma medications, best-corrected visual acuity, and the number of peripheral anterior synechiae quadrants were recorded at baseline and at various time points after surgery.Results: Intraocular pressure decreased significantly from 20.93 ± 6.53 mmHg preoperatively to 15.09 ± 3.63 mmHg (P < 0.001) at 36 months.The number of glaucoma medications was significantly reduced from 2.45 ± 1.18 preoperatively to 1.25 ± 1.55 (P = 0.001) at 36 months.The success rate of the combined surgery was 90.0% at 36 months.The decrease of intraocular pressure exhibited a positive correlation with the baseline intraocular pressure (P < 0.001), while the reduction in the number of glaucoma medications was positively correlated with the baseline number of glaucoma medications (P < 0.001).Best-corrected visual acuity improved from 0.39 ± 0.29 to 0.48 ± 0.34 at 1 month (P = 0.005).There were no vision-threatening complications intraoperatively or postoperatively.Conclusion: The combined surgery has been proven to be effective and safe for patients with primary angle-closure glaucoma in the long term, suggesting that combined surgery may be beneficial for patients with primary angle-closure glaucoma, especially those with long-term and extensive peripheral anterior synechiae.
DOI: 10.7150/ijms.103795
Institutions: Peking University People's Hospital, Peking University
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,337
OpenAlex ID: W4405953658