Year: 2024
Type: article
Abstract: Epitranscriptomics, the study of RNA modifications, has emerged as a critical field in understanding the regulation of gene expression and cellular function. RNA modifications, including N6-methyladenosine (m6A), 5-methylcytosine (m5C), pseudouridine (ψ), and N1-methyladenosine (m1A), play essential roles in RNA stability, splicing, translation, and stress response mechanisms. These modifications are dynamically regulated by a complex machinery of writers, erasers, and readers, which influence RNA metabolism and function across diverse biological processes. In recent years, mounting evidence has linked dysregulated RNA modifications to various diseases, including cancer, neurodegenerative disorders, and viral infections.
Authors: Atiqa Zahra Farooq, Mazhar Farooq, Umber Rauf, Tayyaba Khalid, Muhammad Umair, Atif Abbasi, Farhan Haider Baryar, Mohammad Rahim, Muhammad Mudassar Raza, Ayesha Meerab
Language: English
Topic: RNA modifications and cancer
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4405955913