Nutritional challenges and determinants in children with sickle cell disease in Chhattisgarh, India
Year: 2024
Type: article
Study design: Observational Study
Abstract: BackgroundSickle cell disease (SCD) is one of the commonest single gene disorders recognized as a public health priority. Slow growth is common in children with SCD due to the vicious cycle of malnutrition and infection among them. Increasing knowledge that nutritional problems are fundamental to the severity of the disease has produced interest in promoting dietary supplementation for treating these patients.ObjectiveThe objective of the present study was to assess nutritional status and associated factors in SCD patients registered at the Sickle Cell Institute Chhattisgarh, Raipur, CG, India.MethodsWe reviewed clinical data from documents/secondary records among a cohort of 671 children with SCD 0-18 years oldat the Sickle Cell Institute.ResultsOut of all 671 children included in the study, 380 (56.6%) were male. Underweight, stunting and wasting proportions were 58%, 37.7% and 38.9% respectively. 16% children had chronic malnutrition (low height for age). 62% of the malnourished children were ≥ 11 years old and38% were ≤ 10 . 64% of the children who needed hospitalization were also in the older age group. Chronic malnutrition was significantly higher among children with an O Rh+ blood group (39.8%). 26.7% had sought care in hospital before diagnosis either for blood transfusion or for a vaso-occlusive crisis.ConclusionsA significant proportion of chronic malnutrition was seen among the study population mixed with underweight, stunting and wasting. Older children with an O+Ve blood group had increased risk of hospital admission. Children should get priority for nutritional intervention as adjunct treatment with standard care practice to increase survival chances.
Source: World Nutrition
Authors: Dr ASHISH SINHA, Pradeep Kumar Patra, Prem Sagar Panda
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405966798