Work

Senotherapeutics, Aging, and Age-related Diseases

Year: 2024

Type: conference-abstract

Abstract: Increased translational clinical trials are addressing the utility of senotherapeutic agents as interventions for aging in general and for age-related diseases. Numerous pre-clinical trials have provided a good rationale for human clinical trials which are being increasingly proposed. At present a number of senolytic and senomorphic drugs appear to be safe and tolerable by older persons, hence new human clinical trials directed at efficacy in ameliorating age-related diseases and aging in general are now coming to the fore. This talk will review:1) what are these agents? 2) what are their mechanism(s) of action? and 3) what efficacy have they demonstrated?

Source: Innovation in Aging

DOI: 10.1093/geroni/igae098.1474

Author: Dean Kellogg

Institution: The University of Texas at San Antonio Health Science Center

Language: English

Topic: Telomeres, Telomerase, and Senescence

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,375