Work

A delayed diagnosis of a case with multiple system atrophy

Year: 2024

Type: article

Abstract: BACKGROUND: A patient presented to movement disorder clinic with cognitive complaints, imbalance and prior diagnosis of NPH. The patient underwent ventriculoperitoneal shunt in the past with minimal improvement, a detailed history is suggestive of REM sleep behavioral disorder, autonomic dysfunction including orthostatic hypotension and urinary incontinence. METHOD: Clinical evaluation was notable for bradykinesia, rigidity, truncal and cervical dystonia, shuffling steps, reduced arm swing bilaterally and pink, dusky skin of both hands. RESULT: DaTscan showed reduced uptake of dopamine transporter. CONCLUSION: Evaluation at movement disorder clinic helps early diagnosis of neurodegenerative disorders with subtle findings which allows patients to benefit from available treatments and participation in appropriate clinical trials.

Source: Alzheimer s & Dementia

DOI: 10.1002/alz.093559

Authors: Mohamed Elkasaby, Elliott Hayden, Brian Appleby

Institutions: University Hospitals Cleveland Medical Center, Case Western Reserve University, University Hospitals of Cleveland

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,000