Year: 2024
Type: article
Abstract: Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) is a catchall name for immunologically-based disorders that develop in genetically predisposed persons after exposure to adjuvants such as silicone breast implants.This article summarizes the existing literature on ASIA, focusing on the link between breast implants and the development of autoimmune diseases.Breast implants have grown in popularity in cosmetic surgery since the 1960s, but their use offers significant health risks, such as inflammatory responses and autoimmune problems.The study clarifies research findings on the pathophysiology of ASIA, focusing on the impact of silicone leaks on the immune system and infiltration into surrounding tissues.It intensively examines the processes that cause foreign body reactions and the potential function of adjuvants in triggering the immune response.Review focuses on silicone mobility and the production of bacterial biofilms, both related to prolonged inflammatory reactions.The findings suggest that more research into implant operation techniques is needed to improve understanding of the risks and provide safer choices for patients.The authors underline the importance of raising patient and professional knowledge about the possible hazards of breast implants, as well as encouraging greater research into silicone-free breast reconstruction techniques.
Source: Medical Science
Authors: Aisha Hassan, Sara Hassan, Szymon Bienia, Wafa Al- Batool, Aleksandra Kossakowska, Jakub Leicht, Paweł Godlewski, Klaudia Konieczna, Izabela Zarecka, Anna Gwóźdź-Broczkowska, Bartosz Górecki
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4406077336