Relationship between fluid intake, hydration status and cortisol dynamics in healthy, young adult males
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Previous studies have identified links between fluid intake, hydration related hormones and cortisol measured at one timepoint but have not considered how hydration may influence cortisol dynamics throughout the day. This study assessed associations between hydration status (copeptin, urinary osmolality, urine volume) and habitual fluid intake with cortisol dynamics. Methods: - highest cortisol of all samples), cortisol awakening response (ΔCAR - difference between high morning sample and awakening sample), area under the curve with respect to ground (AUCG) and increase (AUCI), and diurnal cortisol slope (DCS - rate of change in cortisol from awakening to bed). The relationships between fluid intake or hydration status and cortisol dynamics were analyzed by separating participants into fluid intake tertile groups and by regressing cortisol dynamics on the continuous variables of total fluid intake (TFI) or hydration biomarkers. Results: ) (p = 0.99), ΔCAR (p = 0.22), AUCG (p = 0.69) or AUCI (p = 0.18). Urinary hydration markers were not associated with any measures of cortisol dynamics (p > 0.05). These null effects were consistent when controlling for physical activity, sleep, and body fat percentage. Conclusion: In the absence of dehydrating stimuli, measures of fluid intake or hydration status may not be associated with cortisol dynamics in young healthy males.
Authors: Mitchell E. Zaplatosch, Laurie Wideman, Jessica McNeil, Jesse N.L. Sims, William M. Adams
Language: English
Subfield: Behavioral Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,180
OpenAlex ID: W4406080201