Examination of a Novel Nanocompositer's Bioactivity for Use in Dentistry
Year: 2024
Type: article
Abstract: The extended setting time of mineral trioxide aggregate (MTA) is one of its primary drawbacks. An alternative to MTA, Nano Fast Cement (NFC) is a novel nanocomposite with a quick setting time. In order to develop an exceptional dental filler, hydroxyapatite nanoparticles (NHA) were introduced to NFC to examine its impact on setting time, biocompatibility, and bioactivity qualities. X-ray diffraction, scanning electron microscopy, Gilmore needle, and MTT assay were used to evaluate the specimens with 0, 10, and 20 W% hydroxyapatite. The antibacterial evaluation was conducted using Enterococcus faecalis (PTCC 1394). Using phase and microstructural studies, the production of hydroxyapatite was discovered. Both 10 and 20 weight percent prime apatite enhanced the specimens' bioactivity and markedly decreased their toxicity behavior. More HA content resulted in greater bioactivity enhancement and toxicity decrease. These results suggest that the physical properties of NFC were not negatively impacted by the addition of NHA. In vitro, they enhanced the filler's bioactivity.
Source: Galen Medical Journal
Institutions: Mazandaran University of Medical Sciences, Shiraz University, Shiraz University of Medical Sciences, Islamic Azad University, Tehran, Islamic Azad University Pharmaceutical Sciences Branch, Arak University of Medical Sciences, Lorestan University of Medical Sciences, Tabriz University of Medical Sciences, Yasouj University, Dalian Medical University, Zand Institute of Higher Education, Gonabad University of Medical Sciences, University of Münster, University Hospital Münster, Warsaw Management University
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4406087689