Supplementary Table S1-S14 from Genomic and Epigenomic Analysis of Plasma Cell-Free DNA Identifies Stemness Features Associated with Worse Survival in Lethal Prostate Cancer
Year: 2025
Type: supplementary-materials
Abstract: Table S1. Patient characteristics. Table S2. Patients-level clinical treatment and outcome details. Table S3. Mutations detected in patient cell-free DNA by EnhanceAR-Seq. Table S4. Copy number alterations detected in patient cell-free DNA by EnhanceAR-Seq. Table S5. Structural variations detected in patient cell-free DNA by EnhanceAR-Seq. Table S6. Cox regression for progression-free survival with baseline covariates including altered AR enhancer detected in pre-treatment plasma. Table S7. Cox regression for overall survival with baseline covariates including altered AR enhancer in pre-treatment samples. Table S8. Clinical characteristics of the metastatic prostate cancer cohort. Table S9. Patient plasma cell-free DNA methylation sequencing metrics. Table S10. Hypomethylated DMRs in AR/enhancer altered lethal mCRPC patients. Table S11. Hypermethylated DMRs in AR/enhancer altered lethal mCRPC patients. Table S12. Central coverage of transcription factor binding sites (TFBSs) for most accessible transcription factors in AR/enhancer altered lethal mCRPC. Table S13. Central coverage of transcription factor binding sites (TFBSs) for least accessible transcription factors in AR/enhancer altered lethal mCRPC. Table S14. Multivariate Cox regression for progression-free survival.
Authors: Pradeep S. Chauhan, Irfan Alahi, Savar Sinha, Elisa M. Ledet, Ryan Mueller, Jessica Linford, Alexander L. Shiang, Jace Webster, Lilli Greiner, Breanna Yang, Gabris Ni, Ha X. Dang, Debanjan Saha, Ramandeep K. Babbra, Wenjia Feng, Peter K. Harris, Faridi Qaium, Dzifa Y. Duose, Sanchez E. Alexander, Alexander D. Sherry, Ellen B. Jaeger, Patrick J. Miller, Sydney A. Caputo, Jacob J. Orme, Fabrice Lucien, Sean S. Park, Chad Tang, Russell K. Pachynski, Oliver Sartor, Christopher A. Maher, Aadel A. Chaudhuri
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4406114564