A chemically modified DNAzyme-based electrochemical sensor for binary and highly sensitive detection of reactive oxygen species
Year: 2025
Type: article
Abstract: and HClO) produced by cancer cells with high sensitivity across a broad linear range of 1 to 200 nM and a low detection limit in the sub-nanomolar range. The design strategies behind the developed ROS sensing system could also be exploited to create other biosensors with highly sensitive and binary detection to promote clinical research and revolutionize disease diagnostics.
Source: Chemical Science
DOI: 10.1039/d4sc05512h
Authors: Baoting Dou, Hui Shen, Zhimin Li, Huanyu Cheng, Po Wang
Institutions: Jiangsu Normal University, Pennsylvania State University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
Funders: National Science Foundation, University of Pennsylvania, Pennsylvania State University, Natural Science Foundation of Xuzhou City, National Natural Science Foundation of China, Government of Jiangsu Province, Natural Science Foundation of Jiangsu Province, Priority Academic Program Development of Jiangsu Higher Education Institutions
OpenAlex ID: W4406154439