Work

A double-chain based metallomicellar catalyst for aerobic oxidative synthesis of benzimidazoles in water

Year: 2025

Type: article

Abstract: a common amine-N. Complexes Mo2 and Mo3 formed metallomicelle when dispersed in water due to the surfactant presence in their structures, enabling them to uptake organic substrates. The catalytic potential of the complexes was evaluated for the oxidative coupling of benzylamine with 1,2-diaminobenzene to synthesize benzimidazole in neat water using open air as the sole oxidant. The double-chain surfactant-type catalyst Mo3 displayed superior activity compared to the single-chain surfactant-type complex, Mo2. A wide variety of benzimidazoles were synthesized in good to excellent yields under environmentally benign conditions using Mo3 as the catalyst. The practical utility of the process was validated through multi-gram scale-up reactions and recyclability experiments. A plausible mechanism was proposed based on several controlled experiments and literature support.

Source: Dalton Transactions

DOI: 10.1039/d4dt03406f

Authors: Pragyansmruti Sunani, Prabaharan Thiruvengetam, Dillip Kumar Chand

Institution: Indian Institute of Technology Madras

Language: English

Topic: Oxidative Organic Chemistry Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Clean water and sanitation

Open Access status: bronze

Funder: Indian Institute of Technology Madras