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Synthesis, Structural Characterization and In Vitro Leishmanicide and Antifungal Activities Studies of Schiff Base Compounds

Year: 2024

Type: article

Abstract: N, N'-bis (2-nitrophenyl methylene)hexane-1,6-diamine, N, N'-bis (4- nitrophenylmethylene)benzene-1,3-diamine, N, N'-bis (p-nitrophenylmethylene) cyclohexane- 1,2-diamine were synthesize and have been characterized by conventional spectrometry methods (NMR, IR and HR-ESI-MS). Antileishmanicide and antifungal screening showed that, N, N'-bis (2-nitrophenyl methylene) hexane- 1,6-diamine, with MIC of 16.40 mg/L and 125 mg /L respectively, is the most active.

Source: Chemical & Pharmaceutical Research

DOI: 10.33425/2689-1050.1062

Authors: Kangah Niameke Jean-Baptiste, Tuo Nanou Tieba, Ziale Djele Alette Edwige, Kablan Ahmont Landry Claude, Kodjo Charles Guillaume, Ziao Nahosse

Institutions: Université Nangui Abrogoua, Institut National Polytechnique Félix Houphouët-Boigny

Language: English

Topic: Synthesis and Characterization of Heterocyclic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W4406183593

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