Tumor‐Selective Nano‐Dispatcher Enforced Cancer Immunotherapeutic Effects via Regulating Lactate Metabolism and Activating Toll‐Like Receptors (Small 1/2025)
Year: 2025
Type: article
Abstract: Tumor-Selective Delivery In article number 2406870, Zhi-Yue Zhang and co-workers developed a nano-dispatcher to facilitate tumor-selective co-delivery of a monocarboxylate transporter 4 (MCT4) inhibitor and a TLR7/8 agonist. This approach enhances the immunotherapeutic effect by synergistically regulating lactate metabolism and activating dendritic cells.
Source: Small
Authors: Yang Liu, Hui Li, Yan‐Yun Hao, Ling‐Ling Huang, Xia Li, Jing Zou, Shi‐Ying Zhang, Xiao‐Yue Yang, Hong‐Fei Chen, Yi‐Xuan Guo, Yun‐Yan Guan, Zhi‐Yue Zhang
Institution: Shandong University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4406184626