Year: 2025
Type: article
Abstract: Introduction: Xenotransplantation, the transplantation of organs of non-human origin into humans, is a potential long term solution to the chronic shortage of organs currently available for transplantation. Several xenotransplants using porcine organs from pigs that were genetically modified to remove cell-surface antigens that could lead to alloimmunity, have recently been reported, including heart and kidney, with human patients surviving the surgery for an encouraging duration. Donor-derived cell-free DNA (dd-cfDNA) has been validated as a non-invasive biomarker for the detection of rejection in solid organ transplant, and is routinely used in both a surveillance and for cause setting.
Institution: Natera (United States)
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W4406186950