Work

Liver Transplant Outcomes of NMP Allografts with End-Perfusion Lactate Greater or Equal to 2.5 mmol/L

Year: 2025

Type: article

Abstract: Background: Normothermic machine perfusion (NMP) is increasingly used for liver transplantation (LT) to reduce ischemia-reperfusion injury and improve graft outcomes. Allograft lactate clearance thresholds, ranging from < 1.7 mmol/L to 2.5 mmol/L, are commonly used in clinical practice, though their predictive value remains debated. This study aimed to compare LT outcomes based on end- perfusion lactate levels in NMP livers.

Source: American Journal of Transplantation

DOI: 10.1016/j.ajt.2024.12.244

Authors: Stephanie Ohara, Xingjie Li, Kunam Reddy, Amit Mathur, Caroline Jadlowiec, Michelle Nguyen

Institution: Mayo Clinic Hospital

Language: English

Topic: Organ Transplantation Techniques and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,300