Leucocytes and CD4 Counts of Individuals Exposed to Roadside Dust in Ekpoma, Edo State, Nigeria
Year: 2024
Type: article
Study design: Observational Study
Abstract: Roadside dust is a combination of particulate matter generated from vehicular traffic and other human activities along the road.This study investigated the leucocytes and Cluster of Differentiation-4 (CD4) counts of individuals exposed to roadside dust in Ekpoma, Edo State.A total to 50 test subjects aged 18-65 years and of both sexes were recruited for this study, while 50 individuals not exposed to road-side dust served as controls.The leucocytes and CD4 counts were analyzed using Sysmex KX-21N Autoanalyzer and Flow cytometry method respectively.The results obtained revealed the total white blood cell counts of the subjects studied were 5.27±1.60 and 5.22±1.66 for the test and control subjects respectively.With respect to the differential leucocyte count, the mean values of the test and control subjects for NEUT %, LYM % and MXD % were 40.31±9.75 and 38.62±10.0,47.9 ±9.15 and 50.7±9.86,11.66±4.40and 10.7±3.72 respectively.Furthermore, the mean values of the CD4 counts of the test and control subjects were 890.26±266.21 and 850.94±302.13respectively.Statistical comparison of the mean values of total WBC, differential leucocytes count and CD4 counts and road side dust did not reveal any significant difference (p>0.05).With respect to age, gender and duration of exposure to road-side dust, the leucocytes and CD4 counts were not significantly affected.In conclusion, exposure to road dust did not affect the leucocytes and CD4 counts of our study subjects.
DOI: 10.30654/mjia.10029
Authors: Babatope IO, Omoregie OI, Iyevhobu KO
Institution: Ambrose Alli University
Language: English
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4406252282