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Ferric Chloride and DABCO as a Versatile and Effective Catalytic System for Synthesis Thiazolidinedione Phamacophore

Year: 2024

Type: article

Abstract: A mild and efficient procedure for the synthesis of synthetic approach for creating 2, 4-thiazolidinedione derivatives through the Knoevenagel condensation reaction, substituted benzaldehyde with 2,4-thiazolidinedione in ethanol catalysed by Ferric chloride and DABCO as a versatile and effective catalyst. These 2, 4-thiazolidinedione derivatives are significant due to their diverse biological activities’ significant advantages, such as cost-effectiveness, non-toxicity, and operational simplicity and high yield.

Source: Austin Journal of Analytical and Pharmaceutical Chemistry

DOI: 10.26420/austinjanalpharmchem.2024.1173

Authors: Santosh V Padghan, Suraj Ade, Manojkumar Chopade

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W4406253635

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